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Low-calorie sugar alternatives could negatively affect gut health, study finds

Low-calorie sugar alternatives, which had previously been thought to be relatively harmless, may actually have a negative effect on human gut health, according to a new study. All four substances tested in the study – saccharin, sucralose, aspartame and stevia – were found to change the gut microbiome, the collection of microbes in the gut that help protect humans against disease and enable us to digest food. The study, published this month in the medical journal Cell, included 120 healthy adults, who were given the different low-calorie sugar alternatives at levels lower than the acceptable daily intake.

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